- Babakhani, K, Kucinskas, AL, Ye, X, Giles, ED, Sun, Y. Aging immunity: unraveling the complex nexus of diet, gut microbiome, and immune function. Immunometabolism (Cobham). 2025;7 (2):e00061. doi: 10.1097/IN9.0000000000000061. PubMed PMID:40352822 PubMed Central PMC12063687.
- Giles, ED, Cook, KL, Jenschke, RM, Corleto, KA, Landrock, D, Mahmood, TN et al.. Metabolic and transcriptional effects of bazedoxifene/conjugated estrogens in a model of obesity-associated breast cancer risk. JCI Insight. 2025;10 (8):. doi: 10.1172/jci.insight.182694. PubMed PMID:40048260 PubMed Central PMC12016928.
- Corleto, KA, Schedin, P, Kotta, AS, Strandmo, JL, Foster, SM, Lammoglia, N et al.. Targeting the menopause transition with metformin improves breast cancer outcomes, but discontinuation has deleterious effects on metabolic health: Findings from a preclinical model of postmenopausal breast cancer. bioRxiv. 2024; :. doi: 10.1101/2024.11.25.625083. PubMed PMID:39651199 PubMed Central PMC11623501.
- Noh, JY, Han, HW, Kim, DM, Giles, ED, Farnell, YZ, Wright, GA et al.. Innate immunity in peripheral tissues is differentially impaired under normal and endotoxic conditions in aging. Front Immunol. 2024;15 :1357444. doi: 10.3389/fimmu.2024.1357444. PubMed PMID:39221237 PubMed Central PMC11361940.
- Jospe, MR, Liao, Y, Giles, ED, Hudson, BI, Slingerland, JM, Schembre, SM et al.. A low-glucose eating pattern is associated with improvements in glycemic variability among women at risk for postmenopausal breast cancer: an exploratory analysis. Front Nutr. 2024;11 :1301427. doi: 10.3389/fnut.2024.1301427. PubMed PMID:38660060 PubMed Central PMC11039850.
- Corleto, KA, Strandmo, JL, Giles, ED. Metformin and Breast Cancer: Current Findings and Future Perspectives from Preclinical and Clinical Studies. Pharmaceuticals (Basel). 2024;17 (3):. doi: 10.3390/ph17030396. PubMed PMID:38543182 PubMed Central PMC10974219.
- Giles, ED, Purcell, SA, Olson, J, Vrieling, A, Hirko, KA, Woodruff, K et al.. Trends in Diet and Cancer Research: A Bibliometric and Visualization Analysis. Cancers (Basel). 2023;15 (15):. doi: 10.3390/cancers15153761. PubMed PMID:37568578 PubMed Central PMC10417030.
- Sanchez, L, Epps, J, Wall, S, McQueen, C, Pearson, SJ, Scribner, K et al.. SIM2s directed Parkin-mediated mitophagy promotes mammary epithelial cell differentiation. Cell Death Differ. 2023;30 (6):1472-1487. doi: 10.1038/s41418-023-01146-9. PubMed PMID:36966227 PubMed Central PMC10244402.
- Wellberg, EA, Corleto, KA, Checkley, LA, Jindal, S, Johnson, G, Higgins, JA et al.. Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer. Breast Cancer Res. 2022;24 (1):42. doi: 10.1186/s13058-022-01535-x. PubMed PMID:35725493 PubMed Central PMC9208221.
- Kotta, AS, Kelling, AS, Corleto, KA, Sun, Y, Giles, ED. Ghrelin and Cancer: Examining the Roles of the Ghrelin Axis in Tumor Growth and Progression. Biomolecules. 2022;12 (4):. doi: 10.3390/biom12040483. PubMed PMID:35454071 PubMed Central PMC9032665.
- Baine, RE, Johnston, DT, Strain, MM, Henwood, MK, Davis, JA, Reynolds, JA et al.. Noxious Stimulation Induces Acute Hemorrhage and Impairs Long-Term Recovery after Spinal Cord Injury (SCI) in Female Rats: Evidence Estrous Cycle May Have a Modulatory Effect. Neurotrauma Rep. 2022;3 (1):70-86. doi: 10.1089/neur.2021.0055. PubMed PMID:35112109 PubMed Central PMC8804264.
- Schembre, SM, Jospe, MR, Giles, ED, Sears, DD, Liao, Y, Basen-Engquist, KM et al.. A Low-Glucose Eating Pattern Improves Biomarkers of Postmenopausal Breast Cancer Risk: An Exploratory Secondary Analysis of a Randomized Feasibility Trial. Nutrients. 2021;13 (12):. doi: 10.3390/nu13124508. PubMed PMID:34960058 PubMed Central PMC8707938.
- Fabian, CJ, Klemp, JR, Marchello, NJ, Vidoni, ED, Sullivan, DK, Nydegger, JL et al.. Rapid Escalation of High-Volume Exercise during Caloric Restriction; Change in Visceral Adipose Tissue and Adipocytokines in Obese Sedentary Breast Cancer Survivors. Cancers (Basel). 2021;13 (19):. doi: 10.3390/cancers13194871. PubMed PMID:34638355 PubMed Central PMC8508448.
- Glenny, EM, Coleman, MF, Giles, ED, Wellberg, EA, Hursting, SD. Designing Relevant Preclinical Rodent Models for Studying Links Between Nutrition, Obesity, Metabolism, and Cancer. Annu Rev Nutr. 2021;41 :253-282. doi: 10.1146/annurev-nutr-120420-032437. PubMed PMID:34357792 PubMed Central PMC8900211.
- Fabian, CJ, Befort, CA, Phillips, TA, Nydegger, JL, Kreutzjans, AL, Powers, KR et al.. Change in Blood and Benign Breast Biomarkers in Women Undergoing a Weight-Loss Intervention Randomized to High-Dose ω-3 Fatty Acids versus Placebo. Cancer Prev Res (Phila). 2021;14 (9):893-904. doi: 10.1158/1940-6207.CAPR-20-0656. PubMed PMID:34244155 PubMed Central PMC8416797.
- Giles, ED, Wellberg, EA. Preclinical Models to Study Obesity and Breast Cancer in Females: Considerations, Caveats, and Tools. J Mammary Gland Biol Neoplasia. 2020;25 (4):237-253. doi: 10.1007/s10911-020-09463-2. PubMed PMID:33146844 PubMed Central PMC8197449.
- Giles, ED, Brown, IL, MacLean, PS, Pan, Z, Melanson, EL, Heard, KJ et al.. The In Vivo Net Energy Content of Resistant Starch and Its Effect on Macronutrient Oxidation in Healthy Adults. Nutrients. 2019;11 (10):. doi: 10.3390/nu11102484. PubMed PMID:31623184 PubMed Central PMC6835355.
- Presby, DM, Checkley, LA, Jackman, MR, Higgins, JA, Jones, KL, Giles, ED et al.. Regular exercise potentiates energetically expensive hepatic de novo lipogenesis during early weight regain. Am J Physiol Regul Integr Comp Physiol. 2019;317 (5):R684-R695. doi: 10.1152/ajpregu.00074.2019. PubMed PMID:31553623 PubMed Central PMC6879845.
- Sherk, VD, Jackman, MR, Higgins, JA, Giles, ED, Foright, RM, Presby, DM et al.. Impact of Exercise and Activity on Weight Regain and Musculoskeletal Health Post-Ovariectomy. Med Sci Sports Exerc. 2019;51 (12):2465-2473. doi: 10.1249/MSS.0000000000002082. PubMed PMID:31274683 PubMed Central PMC7194137.
- Giles, ED, Jindal, S, Wellberg, EA, Schedin, T, Anderson, SM, Thor, AD et al.. Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer. Breast Cancer Res. 2018;20 (1):50. doi: 10.1186/s13058-018-0974-2. PubMed PMID:29898754 PubMed Central PMC6000949.